Josephine M Egan Selected Research

Alzheimer Disease (Alzheimer's Disease)

1/2024	Association of Plasma Markers of Alzheimer's Disease, Neurodegeneration, and Neuroinflammation with the Choroid Plexus Integrity in Aging.
1/2023	Novel Hominid-Specific IAPP Isoforms: Potential Biomarkers of Early Alzheimer's Disease and Inhibitors of Amyloid Formation.
1/2020	Medium Chain Triglycerides induce mild ketosis and may improve cognition in Alzheimer's disease. A systematic review and meta-analysis of human studies.
5/2019	Correction to: Neurexin 3 transmembrane and soluble isoform expression and splicing haplotype are associated with neuron inflammasome and Alzheimer's disease.
1/2019	Neurexin 3 transmembrane and soluble isoform expression and splicing haplotype are associated with neuron inflammasome and Alzheimer's disease.
1/2019	A Pilot Study of Exenatide Actions in Alzheimer's Disease.
1/2018	Evidence for brain glucose dysregulation in Alzheimer's disease.
1/2015	DNA polymerase β deficiency leads to neurodegeneration and exacerbates Alzheimer disease phenotypes.
11/2014	Prognostic classification of mild cognitive impairment and Alzheimer's disease: MRI independent component analysis.
6/2003	Glucagon-like peptide-1 decreases endogenous amyloid-beta peptide (Abeta) levels and protects hippocampal neurons from death induced by Abeta and iron.

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Josephine M Egan Research Topics

Disease

35	Type 2 Diabetes Mellitus (MODY) 10/2022 - 01/2002
20	Insulin Resistance 11/2022 - 01/2002
20	Obesity 01/2022 - 08/2003
13	Hyperglycemia 03/2024 - 03/2002
12	Inflammation (Inflammations) 02/2024 - 03/2014
11	Alzheimer Disease (Alzheimer's Disease) 01/2024 - 09/2002
7	Body Weight (Weight, Body) 05/2023 - 06/2008
6	Neoplasms (Cancer) 01/2024 - 02/2008
6	Hypoglycemia (Reactive Hypoglycemia) 01/2022 - 12/2008
6	Metabolic Syndrome (Dysmetabolic Syndrome X) 09/2019 - 02/2010
5	Metabolic Diseases (Metabolic Disease) 11/2022 - 01/2008
5	Prediabetic State (Prediabetes) 07/2020 - 10/2013
5	Weight Loss (Weight Reduction) 01/2016 - 10/2008
4	Weight Gain 01/2022 - 01/2012
3	Fatty Liver 01/2021 - 01/2019
3	Diabetes Mellitus 01/2021 - 10/2007
3	Cognitive Dysfunction 01/2020 - 03/2008
3	Abdominal Obesity 01/2016 - 08/2003
3	Glucose Intolerance 10/2007 - 01/2002
2	Hypertension (High Blood Pressure) 01/2023 - 01/2002
2	Ketosis 10/2022 - 01/2020
2	Carcinogenesis 07/2022 - 02/2008
2	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2021 - 03/2003
2	Hypertrophy 01/2020 - 05/2011
2	Insulinoma 03/2016 - 06/2005
2	Hyperinsulinism (Hyperinsulinemia) 11/2014 - 07/2004
2	Peripheral Nervous System Diseases (PNS Diseases) 05/2013 - 03/2002
2	Cardiovascular Diseases (Cardiovascular Disease) 05/2013 - 01/2011
2	Neurodegenerative Diseases (Neurodegenerative Disease) 02/2009 - 03/2002
1	Neuroinflammatory Diseases 01/2024
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2024
1	Treatment-Resistant Depressive Disorder 12/2023
1	Chronic Pain 12/2023
1	Virus Diseases (Viral Diseases) 09/2023
1	Amyloidosis 01/2023

Drug/Important Bio-Agent (IBA)

44	Glucose (Dextrose)FDA LinkGeneric 01/2024 - 01/2002
27	Insulin (Novolin)FDA Link 05/2023 - 01/2002
20	Glucagon-Like Peptide 1 (GLP 1)IBA 01/2020 - 03/2002
10	Hormones (Hormone)IBA 01/2022 - 01/2002
10	Peptides (Polypeptides)IBA 12/2021 - 03/2002
10	Exenatide (Byetta)FDA Link 01/2019 - 03/2002
9	IncretinsIBA 01/2022 - 03/2003
8	Blood Glucose (Blood Sugar)IBA 10/2022 - 09/2002
7	SugarsIBA 02/2024 - 12/2008
6	CannabinoidsIBA 03/2024 - 01/2016
6	LeptinIBA 01/2022 - 08/2003
6	AdiponectinIBA 01/2012 - 08/2003
5	Glucagon-Like Peptide-1 ReceptorIBA 02/2009 - 03/2002
4	Biomarkers (Surrogate Marker)IBA 01/2024 - 03/2014
4	Protein Isoforms (Isoforms)IBA 01/2023 - 01/2019
4	Glucagon (Glukagon)FDA Link 07/2014 - 03/2007
3	CurcuminIBA 11/2022 - 11/2014
3	CytokinesIBA 12/2020 - 07/2010
3	Proteins (Proteins, Gene)FDA Link 01/2019 - 03/2002
3	ResveratrolIBA 11/2014 - 10/2013
2	Growth Differentiation Factor 15IBA 01/2024 - 01/2022
2	Insulin ReceptorIBA 10/2022 - 01/2018
2	EnzymesIBA 12/2020 - 01/2015
2	Triglycerides (Triacylglycerol)IBA 01/2020 - 05/2012
2	Glucagon-Like Peptide-1 Receptor AgonistsIBA 01/2020 - 03/2003
2	InflammasomesIBA 05/2019 - 01/2019
2	PolyphenolsIBA 01/2019 - 11/2014
2	Interleukin-6 (Interleukin 6)IBA 01/2018 - 03/2014
2	Sweetening Agents (Sweeteners)IBA 01/2018 - 01/2016
2	Saline SolutionIBA 07/2014 - 06/2009
2	Sirtuin 1IBA 10/2013 - 10/2013
2	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 05/2013 - 10/2008
2	AdipokinesIBA 01/2012 - 07/2010
2	Glucagon-Like Peptides (Enteroglucagon)IBA 06/2009 - 06/2003
2	Hypoglycemic Agents (Hypoglycemics)IBA 02/2009 - 10/2003
1	PolyaminesIBA 01/2024
1	Urea (Carbamide)FDA LinkGeneric 01/2024
1	Cysteine (L-Cysteine)FDA Link 01/2024
1	CitrullineIBA 01/2024
1	PutrescineIBA 01/2024
1	SpermineIBA 01/2024
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2024
1	Arginine (L-Arginine)FDA Link 01/2024
1	KynurenineIBA 01/2024
1	OrnithineIBA 01/2024
1	Ketamine FDA LinkGeneric 12/2023
1	Hematoxylin (Haematoxylon)IBA 09/2023
1	Eosine Yellowish-(YS) (Eosin)IBA 09/2023
1	SphingolipidsIBA 06/2023
1	CholesterolIBA 01/2023
1	Islet Amyloid PolypeptideIBA 01/2023
1	Amyloid (Amyloid Fibrils)IBA 01/2023
1	Protective AgentsIBA 11/2022
1	AntioxidantsIBA 11/2022
1	empagliflozinIBA 10/2022
1	Neurotransmitter Agents (Neurotransmitter)IBA 10/2022
1	Glutamic Acid (Glutamate)FDA Link 10/2022
1	SodiumIBA 10/2022
1	Reactive Oxygen Species (Oxygen Radicals)IBA 07/2022
1	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2022
1	ProinsulinIBA 12/2021

Therapy/Procedure

8	Therapeutics 01/2017 - 03/2002
4	Gastric Bypass (Roux-en-Y Gastric Bypass) 01/2022 - 05/2011
4	Glycemic Control 01/2018 - 02/2009
1	Gastrectomy 01/2022